José Vilar and Friends Case 27

Hello friends,

I hope you are doing well wherever you are. Here things are not too good but for the moment I am well.

Here is a case just brought from Dr Peset University Hospital in Valencia.

71 year old man who had a syncope and is brought to the Emergency Room. The COVID 19 ARN (RT-PCR) is negative.

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30
Mar 2020
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ACE2 – A rational frontline therapy for COVID-19 summary

On Thursday March 12th, our ESR Connect studio was the epicenter of an important discussion on COVID-19 as we had the privilege to host professor Josef Penninger, world-leading geneticist and immunologist. Prof. Penninger delivered a compelling and important lecture on ACE2 and its role in the ongoing COVID-19 pandemic.

The lecture focused on the discovery and importance of angiotensin converting enzyme 2 (ACE2). Found in many organs, ACE2 positively affects blood pressure, kidney diseases, liver/lung fibrosis, and many other conditions. ACE creates angiotensin II which triggers angiotensin receptors AT1R and AT2R. This reaction can lead to lung edema and severe respiratory diseases, unless ACE2 is present. ACE2 molecules inactivate the bond between ACE and AngII and prevent the receptors from getting activated, thus protecting the organism from coming to harm. Read more…

23
Mar 2020
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José Vilar and Friends Case 26 (Update: Solution!)

Dear colleagues,

we are living dire moments. Our congress in Vienna has been postponed and many of us are subject to severe restrictions in our life, but this will not impede us to continue with our blog, and perhaps help you fill some time if you are isolated.

I would like to send you a case you already know, but with some new features stressed to me by Drs Maldonado and Lorente. Indeed I refer to our very last case (25) the man who had had Lymphoma and an accumulation of fat in the mediastinum: Remember? Read more…

16
Mar 2020
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José Vilar and Friends Case 25 (Update: Solution!)

Dear friends,

Well, we have arrived to case 25 after a bit more than a year. I hope that some of you have learned something and perhaps enjoyed the “game”. Let us continue…

Some days ago two smart radiology residents at Hospital Universitario Dr. Peset, Edgar Lorente and Alfonso Maldonado, presented me this case that has some interesting features. Read more…

02
Mar 2020
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José Vilar and Friends Case 24 (Update: Solution!)

Dear Friends,

Today’s case shows a 35 year old woman with abdominal pain and weight loss.

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17
Feb 2020
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José Vilar and Friends Case 23 (Update: Solution!)

Good day Friends,

here is a case that I kept in my files. Again, only one image. Let me see what you think!

This was a 38 year old man with psychiatric problems.

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03
Feb 2020
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José Vilar and Friends Case 22 (Update: Solution!)

Dear Friends,

After a complicated case (Case 21: Heterotaxia) here is more straightforward one.

A young man with breathing difficulty when doing physical activity.

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20
Jan 2020
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José Vilar and Friends Case 21 (Update: Solution!)

Hello everybody,

I hope you enjoyed your holidays wherever you are. I wish you a wonderful new year!

After case 20 (Tracheobronchomegaly) that was very well interpreted by those who dared to send a diagnosis, here is another challenge.

Preoperatory chest radiographic study. No significant clinical symptoms.

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07
Jan 2020
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José Vilar and Friends Case 20 (Update: Solution!)

Dear friends,

This case was provided to me by Dr Edgar Lorente, a smart radiology resident at Hospital Universitario Dr Peset.

This is a 60 year old male with repeated pulmonary infections. This should not be very hard for you…

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09
Dec 2019
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José Vilar and Friends Case 19 (Update: Solution!)

Dear Friends,

I am spending few days near Barcelona and, of course, I had lunch with my friend José Caceres, master of the blogs. José ( and the Muppet) advised me to show you this case, so here it is.

This is a case that will test your ability to integrate the findings. Lets see…

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25
Nov 2019
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DISCUSSION 7 Comments